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氮吹仪价格因而它是氨基酸

点击次数:1984  发布日期:2016-12-21  【打印此页
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!物质代谢 ! !由于转氨基反应是可逆反应氮吹仪价格,因而它是氨基酸分解、合成及转变过程中的重要反应。 ! !(三)联合脱氨基作用 ! !转氨基反应中只有氨基的转移,而没有真正脱氨。体内氨基酸的脱氨基作用主要是通过联合脱氨基 作用(转氨基作用偶联脱氨基作用)来完成的。 ! !"#转氨酶与谷氨酸脱氢酶的联合脱氨基作用 !!首先,氨基酸与 !酮戊二酸在转氨酶催化下,生成相应的 !酮酸和谷氨酸,然后谷氨酸又在 $谷 酮戊二酸,(图 ( 氨酸脱氢酶作用下,脱去氨基又转变为 !并释放出 %&’))。 图 ( )!联合脱氨基作用 (")转氨酶;(*)谷氨酸脱氢酶 !!这种联合脱氨基作用是可逆的过程,因此,这一过程又是体内合成氨基酸的主要途径。但因必需氨基 酸相应的 !酮酸在体内不能合成,故失去合成必需氨基酸的能力。 ! !*#嘌呤核苷酸循环 !!上述联合脱氨基作用虽然重要,但是在骨骼肌和心肌中 $谷氨酸脱氢酶的活性低。这些组织的氨 基酸难于借上述方式脱氨基,而是通过嘌呤核苷酸循环(+,-./0 /,12034.50 16120)脱氨基。其具体步骤是在 肌肉等组织中氨基酸通过转氨基作用,使草酰乙酸生成的天冬氨酸。天冬氨酸与次黄嘌呤核苷酸( 789) 反应生成腺苷酸代琥珀酸,后者裂解出延胡索酸而生成腺嘌呤核苷酸(:89)。:89又在腺苷酸脱氨酶催 化下脱去氨基再生成 789,最终完成了氨基酸的脱氨基。 789再参加下一轮循环。嘌呤核


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